A new study about multiple sclerosis in IRAN
This is the abstract of our new study about multiple sclerosis that has published in the journal of ectrims ( europian comittee for treatment and research in multiple sclerosis) volume 12 -september 2006:
Relationship between fatigue and physical disability with depression in multiple sclerosis
A. Nourian,M. Saeedian H. Madayeni awal, H. Koshyar, M. Shakeri, (Mashad, IR)
Introduction: Multiple sclerosis (MS) is a neurological illness characterized by various somatic and emotional symptoms, such as physical disability, fatigue, and depression. Depression is a particularly common form of psychopathology in MS patients.
Objective: The aim of the present study was to investigate the effect of fatigue and physical disability on depression in patients with multiple sclerosis.
Methods : We studied 105 out-patients that they completed the following measures: The Beck Depression Inventory scale (BDI), The fatigue Severity Scale (FSS) and The Krutzke Expanded Disability Status Scale (EDSS) .
Results:105 MS patients (73 women and 32 men , mean age 31.03 years , SD 8.19 ) with clinically definite with multiple sclerosis ( Relapsing – remitting 86.7% , Primary progressive 2.9% and Secondary progressive 10.5% ). Mean FSS score of the subjects was 4.78 , SD 1.5 , mean of the beck depression Inventory was 16.83 , SD 7 and mean of the expanded disability status scale was 2.54 , SD 1.31 There was significant correlation between fatigue ( FSS ) and depression ( BDI ) ( r=0.617 , p<0.01 ) and noted lower correlation between Physical Disability( EDSS ) and depression (BDI) (r=0.499 , p<0.01).
Conclusions: The present study sought to examine and clarify the relationship between fatigue, and physical disability with depression in a sample of MS patients. We conclude that depression is very high correlated to fatigue and its correlation to Physical Disability was less than fatigue.